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Clinical Characteristics of Shocks in Patients with implanted cardioverter defibrillator Following COVID-19 Infection
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  • Jianying sun,
  • Juan Ma,
  • Feiyu Wei,
  • Yazhe Ma,
  • Xi Zhang,
  • Xiaolong Gao,
  • Tao Ma,
  • Jia Guo,
  • Xiuhua Li,
  • Jie Fan
Jianying sun
First People's Hospital of Yunnan

Corresponding Author:[email protected]

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Juan Ma
First People's Hospital of Yunnan
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Feiyu Wei
First People's Hospital of Yunnan
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Yazhe Ma
First People's Hospital of Yunnan
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Xi Zhang
First People's Hospital of Yunnan
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Xiaolong Gao
First People's Hospital of Yunnan
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Tao Ma
First People's Hospital of Yunnan
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Jia Guo
First People's Hospital of Yunnan
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Xiuhua Li
First People's Hospital of Yunnan
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Jie Fan
First People's Hospital of Yunnan
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Abstract

Background and Aims: The relationship between SARS-CoV-2 infection and ICD shock remains unclear. We analyzed the characteristics of patients received shocks after SARS-CoV-2 infection to explore causes of these shocks to provide information for subsequent treatment. Methods: We retrospectively analyzed data from seven patients who hospitalized the First People’s Hospital of Yunnan Province between December 2022 and January 2023 after experiencing ICD shock or ventricular arrhythmias following SARS-CoV-2 infection. We collected baseline information i.e., age and sex, device type, arrhythmia type, comorbidities, etc to analyze the causes of electrical shocks. Results: All patients’ devices were implanted in our hospital. The patients’ mean age was 67±10 years. Four underwent implantation for primary prevention, and three for secondary prevention. These patients received 80 ICD shocks after SARS-CoV-2 infection, 71 (88.75%) nine (11.25%) of which were treatment for ventricular tachycardia and atrial fibrillation, respectively. There were 54 antitachycardia pacing(ATP) treatments, which forty-eight arrhythmic events were terminated through antitachycardia pacing and six not. Laboratory tests conducted upon admission revealed that six patients had blood potassium levels below 4.0 mmol/L. Five patients had blood calcium levels below 2.11 mmol/L. Four of seven patients had elevated troponin concentrations (0.030–0.297 ng/mL). All patients had significantly elevated N-terminal pro-B-type natriuretic peptide levels (608.8–25,758 pg/mL). Six patients had a QT interval of > 440 ms and a mean QT interval of 460±46 ms. Conclusion: SARS-CoV-2 infection may be associated with ICD shock. Clinicians should pay close attention to patients with implanted devices after SARS-CoV-2 infection and actively eliminate arrhythmogenic triggers to minimize the likelihood of ICD shock.