Non-invasive Capillary Mapping in Skin Tumors Located in Arbitrary Areas
of Human Body
- Anastasia Guryleva,
- Alexander Machikhin,
- Ekaterina Orlova,
- Evgeniya Kulikova,
- Mikhail Volkov,
- Gayane Gabrielian,
- Ludmila Smirnova,
- Mariya Sekacheva,
- Olga Olisova,
- Ekaterina Rudenko,
- Olga Lobanova,
- Tatiana Demura
Anastasia Guryleva
FGBUN Naucno-tehnologiceskij centr unikal'nogo priborostroenia Rossijskoj akademii nauk
Corresponding Author:[email protected]
Author ProfileAlexander Machikhin
FGBUN Naucno-tehnologiceskij centr unikal'nogo priborostroenia Rossijskoj akademii nauk
Author ProfileEkaterina Orlova
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileEvgeniya Kulikova
FGBUN Naucno-tehnologiceskij centr unikal'nogo priborostroenia Rossijskoj akademii nauk
Author ProfileMikhail Volkov
FGBUN Naucno-tehnologiceskij centr unikal'nogo priborostroenia Rossijskoj akademii nauk
Author ProfileGayane Gabrielian
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileLudmila Smirnova
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileMariya Sekacheva
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileOlga Olisova
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileEkaterina Rudenko
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileOlga Lobanova
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileTatiana Demura
Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova
Author ProfileAbstract
Non-invasive, rapid and robust diagnostic techniques for clinical
screening of tumors located in arbitrary areas of the human body are in
demand. To address this challenge, we analyzed the feasibility of vessel
mapping by means of time-lapse digital microscopy for assessing vascular
patterns within malignant and benign tumors. The proposed hardware and
software were approved in a clinical study involving 30 patients with
tumors located in legs, torso, arms, and head. High-contrast and
detailed vessel maps within both benign and malignant tumors were
obtained. We demonstrated that capillary maps are consistent and can be
interpreted using well-established dermoscopic criteria for the vascular
morphology. Vessel mapping provides valuable details, which may not be
available in dermoscopic images and can aid in determining whether a
tumor is benign or malignant. We believe that the proposed approach may
become a valuable tool in the preliminary cancer diagnosis and is
suitable for large-scale screening.Submitted to Journal of Biophotonics 06 Jun 2024Assigned to Editor
06 Jun 2024Submission Checks Completed
06 Jun 2024Review(s) Completed, Editorial Evaluation Pending
04 Jul 2024Editorial Decision: Revise Major
01 Aug 20241st Revision Received
01 Aug 2024Submission Checks Completed
01 Aug 2024Assigned to Editor
01 Aug 2024Reviewer(s) Assigned
01 Aug 2024Review(s) Completed, Editorial Evaluation Pending
25 Aug 2024Editorial Decision: Revise Minor
05 Sep 20242nd Revision Received
06 Sep 2024Submission Checks Completed
06 Sep 2024Assigned to Editor
06 Sep 2024Review(s) Completed, Editorial Evaluation Pending
06 Sep 2024Editorial Decision: Accept