Successful treatment of chest NUT-carcinoma in a paediatric patient with
a novel NUTM1 rearrangement: case report and review of literature
Abstract
NUT carcinoma (NC) is an exceedingly rare and poorly differentiated
carcinoma characterised by BDR4:NUTM1 gene translocation. It typically
affects young adults, and due to its dismal clinical course,
standardized therapeutic recommendations are lacking. In this study, we
present a successful multimodal treatment approach for a 13-year-old boy
diagnosed with primary chest NC harboring a novel NUTM1 rearrangement,
achieving complete continuous remission 21 months after diagnosis.