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Paraneoplatic pruritus in a 7-year-old Slovak warmblood with malignant round cell tumour.
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  • Natália Rovňanová,
  • Veronika Kostolániová,
  • Katarína Lešková,
  • Sandra Hurta-Csizmár,
  • Zdeněk Žert
Natália Rovňanová
University of Veterinary Medicine and Pharmacy in Kosice

Corresponding Author:[email protected]

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Veronika Kostolániová
University of Veterinary Medicine and Pharmacy in Kosice
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Katarína Lešková
Comenius University in Bratislava Jessenius Faculty of Medicine in Martin
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Sandra Hurta-Csizmár
Comenius University in Bratislava Jessenius Faculty of Medicine in Martin
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Zdeněk Žert
University of Veterinary Medicine and Pharmacy in Kosice
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Abstract

A seven year old Slovak warmblood gelding, used as a police horse, initially presented to the refferal clinic when it was five years old, with an itching keloid on the distal limb, requiring surgical removal. After surgical removal of the keloid and successful closure of the skin, it was necessary to maintain bandaging the healed wound to prevent self mutilation as the healed surgical site remained pruritic post operatively. After two years, the horse presented to the clinic again with pruritic and alopetic regions of the head, neck, limbs and base of the tail. Attempts to find the cause of dermal iritation included dermatological, parazitological, microbiological and ultrasonographic examination. Treatment with corticosteroids, antiparasitics and antibiotics were not succesfull. Further investigation due to the horse's worsening general status led to the finding of marked pleural effusion. Cytology of the pleural fluid confirmed there was, as suspected, neoplastic changes in the thoracic cavity. Furthermore there were gross pathological changes of the lymphatic tissue of the cranial mediastinum, surroundings of the aorta in the thoracic cavity and lymph nodes of the abdominal cavity. Histolology of the lymphatic nodes found poorly differentiated round cell tumours. Histopathological findings confirmed there was a very aggressive form of lymphoma. The pruritus, generalised moth-eaten alopecia and self-mutilation were the first symptoms of the terminal disease in this case.
04 Aug 2023Submitted to Equine Veterinary Education
04 Aug 2023Submission Checks Completed
04 Aug 2023Assigned to Editor
18 Oct 2023Reviewer(s) Assigned
07 May 2024Editorial Decision: Revise Minor
28 May 2024Submission Checks Completed
28 May 2024Assigned to Editor
19 Aug 2024Review(s) Completed, Editorial Evaluation Pending
11 Nov 2024Editorial Decision: Revise Minor
18 Nov 20243rd Revision Received
18 Nov 2024Submission Checks Completed
18 Nov 2024Assigned to Editor
18 Nov 2024Review(s) Completed, Editorial Evaluation Pending
18 Nov 2024Editorial Decision: Accept