Abstract Background: The primary breast sarcoma (PBS) was described in 1887. It was a generic term given to malignant breast tumors. The presentation of a sarcoma of the breast, it is a palpable, growing rapidly mass, with or without nipple discharge, or palpable axillary lymph nodes. The PBS can form masses up to 30cm in diameter. There are many risks factors for developing sarcoma of the breast. Clinical Case: A 57-year-old female presented with a 30 x 30cm tumor of the right breast, bleeding with necrosis of two years evolution. biopsy of the lesion is taken where moderately differentiated chondrogenic sarcoma is reported. Wide resection plus chest wall reconstruction (dorsal flap rotation plus partial thickness graft) was performed. A 45 x 40 cm right chest wall tumor is observed, intraoperative without palpable lymphadenopathy. She discharged from the hospital and continues to be monitored. Conclusion: Breast chondrosarcoma is rare and only a few cases are reported in the literature. The role of adjuvant therapy in these patients is still unclear due to the unusual nature of this tumor.