The aim of this study is to propose an information-theoretic framework for compressed sensing (CS)-independent component analysis (ICA) algorithms that can be used for the joint recovery of sparse biosignals. The proposed framework supports real-time patient monitoring systems that enhance the detection, tracking, and monitoring of vital signs remotely via wearable biosensors. Specifically, we address the problem of sparse signal recovery and acquisition in wearable biosensor networks, where we present a new analysis of CS-ICA algorithms from an information theory perspective to compute the sampling rate required to recover sparse biosignals corrupted by motion artifacts and interference, which to the best of our knowledge, has not been studied before. Our analysis and examples indicate that the proposed approach helps to develop low-cost, low-power edge computing devices while improving data quality and accuracy for a given measurement. We also show that, under noisy measurement conditions, the CS-ICA algorithm can outperform the standard CS method, where a biosignal can be retrieved in only a few measurements. By implementing the sensing framework, the error in reconstructing biosignals is reduced, and a digital-to-analog converter operates at low-speed and low-resolution.