We might have to live with COVID-19 until 2025 according to a recent report published in Science! But if we act smartly, the adverse consequence of living with the virus could be minimized. Currently, many states in the United States are seeing spiking cases on a daily basis due to their inadequate policy responses to COVID-19. This paper promotes more research on improving SEIR modeling as it will play a critical role in facilitating the decision-making on promoting and implementing appropriate public health and social interventions. Hopefully, policymakers will listen to science and enact and implement adequate policy responses in combating the COVID-19 pandemic in each of the states across the United States so that we can win this “war” and be well prepared for the promising future.

This is a short article, focusing on promoting more study on SEIR modeling by leveraging rich data and machine learning. We believe that this is extremely critical as many regions at the country or state/provincial levels have been struggling with their public health intervention policies on fighting the COVID-19 pandemic. Some recent published papers on mitigation measures show promising SEIR modeling results, which could shred the light for other policymakers at different community levels. We present our perspective on this research direction. Hopefully, we can stimulate more studies and help the world win this “war” against the invisible enemy “coronavirus” sooner rather than later.