The aim of the study was to evaluate Photobiomodulation (PBM) as an analgesic alternative following endodontic instrumentation. The patient received single-session endodontic treatment on both upper right molars. After standard treatment, PBM was applied to tooth 17, while tooth 16 underwent a simulation. At the end of the procedures, the patient received a Visual Analog Scale to record pain at 4, 8, and 12 hours post-treatment, along with analgesics for use only in case of maximum pain. After 24 hours, a reassessment was conducted. There was a reduction of over 50% in spontaneous pain parameters at all time points, reaching zero at 4 hours. There was a reduction of over 50% in vertical percussion and about 29% in horizontal percussion. Palatal palpation showed an increase of 36%. There was no need for analgesic use. It is concluded that PBM may be an analgesic alternative for post-endodontic instrumentation spontaneous pain.

The objective of this study is to evaluate the effect of photobiomodulation (PBM) on pain control during pterygomandibular puncture. A patient received anesthesia on both sides of the mouth in a randomized manner. On the right side, an 808nm infrared low-level laser was applied before local anesthesia. On the left side, a sham laser was applied using the same technique. There was a 50% reduction in pain levels on the PBM-treated side compared to the sham PBM side, as measured by the visual analog scale. Sensitivity tests revealed that anesthesia was more effective on the PBM side. There was no significant difference in blood pressure before and after anesthesia on either side. While these findings are based on a single case report, they suggest that photobiomodulation before anesthesia may alleviate puncture pain associated with anesthesia. Nevertheless, further well-designed clinical trials are necessary to confirm the effectiveness of this complementary therapy.