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Role of atopic dermatitis management in the prevention of food allergy
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  • Elizabeth Huiwen Tham,
  • Kiwako Yamamoto-Hanada,
  • Agnes Sze Yin Leung,
  • Yukihiro Ohya
Elizabeth Huiwen Tham
National University of Singapore Yong Loo Lin School of Medicine

Corresponding Author:[email protected]

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Kiwako Yamamoto-Hanada
Kokuritsu Kenkyu Kaihatsu Hojin Kokuritsu Seiiku Iryo Kenkyu Center Byoin Allergy Center
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Agnes Sze Yin Leung
The Chinese University of Hong Kong Department of Paediatrics
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Yukihiro Ohya
Kokuritsu Kenkyu Kaihatsu Hojin Kokuritsu Seiiku Iryo Kenkyu Center Byoin Allergy Center
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Abstract

Food allergy is postulated to originate from cutaneous sensitization through a disrupted skin barrier, particularly in atopic dermatitis (AD). Strategies for food allergy prevention currently centre around early allergic food introduction, but there is now increasing evidence for the role of early skin barrier restoration in the form of prophylactic emollient therapy and early aggressive, proactive treatment of established AD for food allergy prevention. Research gaps that remain to be addressed include the type of emollient or anti-inflammatory medication which confers the greatest efficacy in preventive or proactive skin treatment respectively, the duration of therapy, and the window of opportunity for these interventions.
Submitted to Pediatric Allergy and Immunology
24 Jan 20241st Revision Received
25 Jan 2024Submission Checks Completed
25 Jan 2024Assigned to Editor
25 Jan 2024Review(s) Completed, Editorial Evaluation Pending
02 Feb 2024Editorial Decision: Accept