Laparoscopic hepatectomy for primary hepatocellular carcinoma located at
favorable location can stabilize the short-term and long-term outcome
during the development period in a tertiary hospital:
Abstract
Introduction Laparoscopic hepatectomy (LH) for hepatocellular
carcinoma (HCC) has been well-known for its advantages in the past 10
years, but little is known regarding its oncologic outcomes while the
technique is being developed at an institution. This study aimed to
evaluate the safety and effectiveness of LH for patients with primary
HCC at favorable locations during the development period.
Methods We retrospectively reviewed patients diagnosed with
primary HCC that underwent hepatectomy between January 2013 and December
2019 at Hualien Tzu Chi Hospital. Patients with HCC at favorable
locations (anterolateral segments) were collected and divided into
laparoscopic and open hepatectomy (OH) groups. Long-term oncologic
outcomes, including overall, and disease-free survival and postoperative
short-term outcomes were analysed. Results The review included
159 patients, and among which 42 and 44 patients with HCC in favorable
locations were underwent open and laparoscopic hepatectomies. There were
no significant differences in intraoperative blood loss, major
complication rate, and 90-day mortality rate. The laparoscopic group had
a shorter postoperative hospital stay, and lower 90-day readmission
rate. There were no significant differences in overall survival and
disease-free survival. Conclusion LH for favorably located HCC
can stabilize the short-term outcome and long-term outcome during the
development period.