Essential Site Maintenance: Authorea-powered sites will be updated circa 15:00-17:00 Eastern on Tuesday 5 November.
There should be no interruption to normal services, but please contact us at [email protected] in case you face any issues.

loading page

The association between enteral feeding with survival of critical patients with COVID-19 patients
  • +10
  • Maryam Gholamalizadeh,
  • Zahra Salimi,
  • Khadijeh Abbasi Mobarakeh,
  • Zahra Mahmoudi,
  • Shirin Tajadod,
  • Mehdi Moosavi,
  • Farkhondeh Alami,
  • Bojlul Bahar,
  • Saeid Doaei,
  • Sara khoshdooz,
  • Masoume Rahvar,
  • Somayeh Gholami ,
  • Masoume Pourtaleb
Maryam Gholamalizadeh
Shahid Beheshti University of Medical Sciences
Author Profile
Zahra Salimi
Ahvaz Jundishapur University of Medical Sciences
Author Profile
Khadijeh Abbasi Mobarakeh
Isfahan University of Medical Sciences
Author Profile
Zahra Mahmoudi
Hamadan University of Medical Sciences
Author Profile
Shirin Tajadod
Iran University of Medical Sciences
Author Profile
Mehdi Moosavi
Hamadan University of Medical Sciences
Author Profile
Farkhondeh Alami
Urmia University of Medical Sciences
Author Profile
Bojlul Bahar
University of Central Lancashire
Author Profile
Saeid Doaei
Shahid Beheshti University of Medical Sciences

Corresponding Author:[email protected]

Author Profile
Sara khoshdooz
Guilan University of Medical Sciences
Author Profile
Masoume Rahvar
Guilan University of Medical Sciences
Author Profile
Somayeh Gholami
Guilan University of Medical Sciences
Author Profile
Masoume Pourtaleb
Guilan University of Medical Sciences
Author Profile

Abstract

Background: Coronavirus disease 2019 (COVID-19) results in several complications and mortality in ICU patients. The effect of enteral nutrition on the survival of COVID-19 patients in the ICU has been investigated in limited instances. The aim of this study is to investigate the association of enteral feeding with biochemical and pathological indices associated with mortality in COVID-19 patients. Methods: This case-control study was conducted on 240 patients with COVID-19 hospitalized in the ICU including 120 eventually dead patients as the cases and 120 discharged patients as the controls. All of the patients received enteral nutrition. Data on general information, anthropometric measurements, and the results of lab tests were collected. Results: The recovered patients received significantly more high protein (60.8% vs. 39.6%, P=0.004) and high volume (61.6% vs. vs. 42.3%, P=0.005) formula compared to the dead patients. Mortality was inversely associated with high volume (OR:0.45 CI95%, P=0.008) and high protein formula (OR:0.42 CI95%, P=0.003). The results remained significant after adjusting for age and sex. Further adjustment for underlying diseases and smoking, BMI, and APACHII did not change the results. Conclusion: The findings of the study showed that there was a significant inverse association between mortality and high volume and high protein formula in COVID-19 patients that warrants further investigation.
12 Aug 2023Submitted to Immunity, Inflammation and Disease
17 Aug 2023Submission Checks Completed
17 Aug 2023Assigned to Editor
21 Aug 2023Review(s) Completed, Editorial Evaluation Pending
23 Aug 2023Reviewer(s) Assigned
19 Feb 2024Review(s) Completed, Editorial Evaluation Pending
12 Apr 2024Editorial Decision: Accept