Objectives. To estimate postpartum depression at two months (PPD) prevalence and its related risk factors. Design. Multicentre prospective cohort study. Setting. France. Population or sample. Representative sample of 7,133 women participating to the French National Perinatal Survey (ENP) over one week in March 2021. Methods. Data on maternal characteristics, course of pregnancy/delivery, and child’s health were collected from face-to-face interviews in maternity wards and/or medical records, and a self-questionnaire (including the Edinburgh Postnatal Depression Scale (EPDS)) at two months postpartum. Women with an EPDS score >=13 were considered to have PPD. Poisson regression models with robust variance were used to estimate adjusted prevalence ratios (aPR) for PPD. Main Outcome Measures. PPD Results. PPD prevalence at two months was 16.7% (95%CI[15.7-17.7]). Factors significantly associated with PPD were: i/ age<=29 or >=40 years (maximum aPR=1.41 95%CI[1.12-1.77] obtained for 15-24 year-olds vs 35-39 year-olds), ii/ being born in North Africa (1.29[1.02-1.64] vs France), iii/ having a lower level of health literacy (1.23[1.14-1.35]), iv/ having a history of psychological (1.45[1.24-1.69]) or psychiatric (1.52[1.23-1.88]) care since adolescence (vs none), v/ receiving little/no support or good support during pregnancy (1.80[1.52-2.14] and 1.31[1.15-1.48] vs. receiving very good support), vi/ reporting feelings of sadness (1.92[1.65-2.25]), anhedonia (1.69[1.36-2.11]) or both (2.61[2.26-3.01]) during pregnancy (vs none of these feelings), vii/ having had an instrumental vaginal delivery (1.18[1.01-1.38] vs spontaneous vaginal delivery). Conclusions. Our findings on PPD (prevalence and risk factors) could guide policies on early identification and preventive support for women in the perinatal period.

Objective To study the impact of the SARS-CoV-2 pandemic and the first lockdown in France on voluntary changes by pregnant women in the medical monitoring of their pregnancy. Study population Adult (>18 years old) pregnant women during the first lockdown (March-May 2020), living in France, and participating in an access panel of internet users. Design and Settings A cross-sectional study was conducted in July 2020 using a web-questionnaire completed by 500 pregnant women selected by quotas sampling (age group, socio-professional category, region of residence at the time of the lockdown, and parity). Methods A robust variance Poisson regression model was used to estimate adjusted prevalence ratios (aPRs). A manual stepwise descending approach was applied to obtain the final model. Main Outcome Measures Voluntary postponement or foregoing of pregnancy monitoring. Results Almost one women of five (23.4%) reported having voluntarily postponed or foregone at least one consultation or pregnancy check-up during the lockdown. Women who were professionally inactive (aPR=1.98, CI95%[1.24-3.16]), who had experienced serious disputes or violence during the lockdown (1.47, [1.00-2.16]), who felt they received little or no support (1.71, [1.07-2.71]), and those who changed health professionals during the lockdown (1.57, [1.04-2.36]) were all more likely to have voluntarily changed their pregnancy monitoring. Higher level of worry about the pandemic was associated with a lower probability of voluntarily changing pregnancy monitoring (0.66, [0.46 -0.96]). Conclusions Our results can guide prevention and support policies for pregnant women in the current and future pandemics. Financing Santé publique France