New SARS-CoV-2 variants accumulate positive electric residues in the
crucial regions of spike glycoprotein S
Abstract
In the monthly reported by the European Centre for Disease Prevention
and Control virus variants, the increasing tendency in the number of
positively loaded residues was observed. The formal charge of 34
SARS-CoV-2 lineages since September 2020 to June 2021 was analyzed. The
point mutations or small insertions were considered in the crucial for
viral infection regions of the spike glycoprotein (S). The most
frequently observed were positive mutations, especially D614G and E484K,
located in the region of S1/S2 junction, and in the receptor binding
domain (RBD), respectively.