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Electrochemical Cascade Annulation for the Synthesis of 3-Phenylsulfanylquinoline Derivatives Under Mild Conditions
  • +4
  • Ke Li,
  • Ming-Zhong Guo,
  • Zhuo Chen,
  • Hao-Ran Li,
  • Weisi Guo,
  • Ming Li,
  • Lin-Bao Zhang
Ke Li
Qingdao University of Science and Technology
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Ming-Zhong Guo
Qingdao University of Science and Technology
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Zhuo Chen
Qingdao University of Science and Technology
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Hao-Ran Li
Qingdao University of Science and Technology
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Weisi Guo
Qingdao University of Science and Technology
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Ming Li
Qingdao Univ Sci & Technol, State Key Lab Base Ecochem Engn, Coll Chem & Mol Engn, 53 Zhengzhou Rd, Qingdao 266042, Peoples R China
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Lin-Bao Zhang
Qingdao University of Science and Technology

Corresponding Author:[email protected]

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Abstract

An efficient electrochemical approach has been developed for the construction of 3-phenylsulfanylquinoline derivatives by treating phenylethynylbenzoxazinanones with aryl disulfide in an undivided cell. The protocol provided a convenient route to functionalized quinolines with good functional group tolerance. Moreover, it does not require any metal catalysts or additives, furnishing a series of biological quinolines in moderate to good yields.
31 Jan 2024Submitted to Chinese Journal of Chemistry
03 Feb 2024Submission Checks Completed
03 Feb 2024Assigned to Editor
03 Feb 2024Review(s) Completed, Editorial Evaluation Pending
04 Feb 2024Reviewer(s) Assigned
18 Mar 20241st Revision Received
20 Mar 2024Submission Checks Completed
20 Mar 2024Assigned to Editor
20 Mar 2024Review(s) Completed, Editorial Evaluation Pending
29 Mar 2024Editorial Decision: Accept