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Successful remission of a recurrent osteosarcoma in the second and third metacarpal bones of a warmblood gelding after radiation therapy.
  • +5
  • M. Laekeman,
  • Maarten Haspeslagh,
  • Maarten Oosterlinck,
  • Katrien Vanderperren,
  • A. Soukup,
  • E. Rooms,
  • Ann Martens,
  • M. Gruyaert
M. Laekeman
Universiteit Gent Faculteit Diergeneeskunde

Corresponding Author:[email protected]

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Maarten Haspeslagh
Universiteit Gent Faculteit Diergeneeskunde
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Maarten Oosterlinck
Universiteit Gent Faculteit Diergeneeskunde
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Katrien Vanderperren
Universiteit Gent Faculteit Diergeneeskunde
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A. Soukup
Equinox Healthcare GmbH
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E. Rooms
EquiTom Equine Clinic
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Ann Martens
Universiteit Gent Faculteit Diergeneeskunde
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M. Gruyaert
EquiTom Equine Clinic
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Abstract

A fifteen-year-old warmblood gelding was presented with recurrence of a histologically confirmed osteosarcoma of the left second and third metacarpal bones three years after initial diagnosis and treatment. Initially, surgical excision was performed, followed by local injection of carboplatin 11 weeks later. The horse was sound after surgery and was used for low level dressage and jumping. Three years later, the horse developed acute onset of lameness in the left forelimb and a painful soft tissue swelling at the proximomedial metacarpal region. Radiographs showed a spiculated periosteal reaction on the medial aspect of the third metacarpal bone, indicating re-activation of the lesion. Stereotactic radiation therapy was performed with a protocol consisting of three fractions under general anaesthesia (Mo-We-Fr schedule), and a total dose of 30 Gy. The technique used was volumetric modulated arc therapy guided by cone beam computed tomography for daily positioning. Following the radiation therapy, the horse became sound at walk and one month later, it became sound at trot. Follow-up by veterinary examination eighteen months after final treatment revealed no lameness at walk and trot, and a stable radiographic appearance.
20 Mar 2024Submitted to Equine Veterinary Education
20 Mar 2024Submission Checks Completed
20 Mar 2024Assigned to Editor
11 Jun 2024Review(s) Completed, Editorial Evaluation Pending
22 Jul 20241st Revision Received
22 Jul 2024Submission Checks Completed
22 Jul 2024Assigned to Editor
04 Aug 2024Reviewer(s) Assigned
05 Aug 2024Review(s) Completed, Editorial Evaluation Pending
24 Aug 2024Editorial Decision: Revise Minor
24 Aug 20242nd Revision Received
27 Aug 2024Submission Checks Completed
27 Aug 2024Assigned to Editor
27 Aug 2024Review(s) Completed, Editorial Evaluation Pending
27 Aug 2024Editorial Decision: Accept