This paper features the realization of CMOS millimeter-wave high-performance filters with multiple transmission zeros (TZs) employing right-/left-handed Πnetworks. First, the design methods for low pass filter (LPF) with two TZs and high pass filter (HPF) with one TZ using righthanded and left-handed networks are proposed, respectively. In both cases, the networks are analyzed, and the design equations are derived. Furthermore, for both filters, electromagnetic models are proposed and verified by on-chip prototypes on 180nm CMOS technology. The LPF prototype has a measured insertion loss of < 0.6 dB from dc to 60 GHz, a cutoff frequency of 77.7 GHz with two TZs at 100 GHz and 180 GHz. The HPF prototype has a measured insertion loss <1.05 dB from 60 to 147 GHz, a cutoff frequency of 46.9 GHz with one TZ at 33 GHz. Furthermore, a design method for band pass filters (BPFs) is proposed by cascading the LPF and HPF achieving a BPF with three TZs. After EM verification, three prototypes were fabricated on-chip exhibiting three TZs and 3-dB fractional bandwidths of 28%, 41%, and 58%. The corresponding measured insertion losses were 2.5 dB, 1.95 dB, and 1.5 dB, respectively. Also, the corresponding fabricated chip sizes were 0.045 mm2 , 0.046 mm2 , and 0.054 mm2 , respectively.