Abstract
Infantile myofibromatosis (IM) is a disorder characterized by
proliferation of benign myofibroblastic tumors that typically manifest
as solitary or multiple nodules in the skin, muscle, bone, subcutaneous
tissues, and visceral organs and can pose significant morbidity and
mortality risks, particularly in cases involving visceral organs or
causing functional impairment. These soft tissue lesions present before
age two and can undergo spontaneous regression or are amenable to
surgical resection. Successful clinical management with low dose
metronomic chemotherapy (Methotrexate and Vinblastine) is possible and
can treat extensive disease as seen in our patient.