Abstract: The current study was carried out in areas of the Darrang District of Assam, India’s North-Eastern state, to collect data on traditional plants used. The study region was chosen because of the varied groups that have sufficient knowledge about medicinal plants used by the indigenous people in the area. Residents and practitioners in the area were questioned about their knowledge of medicinal plants. According to the findings, 35 percent of the tribes in the Darrang district used medicinal herbs in their homes in a variety of ways, both for nutritional purposes and for traditional healing processes. Total 60 plant species belonging to 42 different families used as herbal remedies for the treatment of various diseases such as skin diseases, stomach problems, dysentery and diarrhea, wounds and cuts, insect or snake bites, boils, jaundice, fever and cough, and throat problem, etc. from the investigator result states that the major parts of the plant used were 46% Leaves, 1.4% flowers, 5.7% fruits, 11.5% seeds, 4.3% barks, 1.4% rhizomes, 1.4% stem, 1.4% roots, 2.8% whole plants, 5.7% aerial part, 2.8% flora body, 4.3% tender shoot, 1.4% leaves base, 4.3% oils, 1.4% nuts, 1.4% straw, 1.4% cloves and 1.4% latex. The most used plant parts for curing disease are leaves followed by seeds, fruits, stems, barks, rhizomes, roots, and flowers. Leaves are made into a paste, warmed and applied or made into juice mixed with water and administered it. Keyword: Darrang District, Medicinal Plants, North Eastern State, Traditionally used