Volumetric Magnetic Resonance Imaging Study Of The Anterior Cingulate
Cortex And Caudate Nucleus In Obsessive-Compulsive Personality Disorder
Abstract
The present study measured the anterior cingulate cortex (ACC) and
caudate nucleus (CN) volumes of patients diagnosed with
obsessive-compulsive personality disorder (OCPD) and compared them with
healthy controls with an aim to investigate its neuroanatomy of. The
Sociodemographic and Clinical Data Form, Beck Anxiety Scale (BAS), Beck
Depression Scale (BDS), and Frost Multidimensional Perfectionism Scale
(FMPS) were administered to 18 healthy controls and 16 patients
diagnosed with OCPD. Volumetric measurements of the right/left ACC and
CNs were performed for all the participants through brain magnetic
resonance imaging. There was no significant difference between patients
and controls by ACC and CN volumes. BAS, BDS, and FMPS scale scores in
the patient group were statistically higher compared to the control
group. Volumetric changes in the ACC and CN do not play a role in the
pathophysiology of OCPD. Functional imaging techniques may be useful in
explaining the likely role of these regions in the etiopathogenesis of
the disease.