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Qianqiong Wang
Public Documents
1
Fast multiphoton microscopic imaging joint image super-resolution for automated Gleas...
Xinpeng Huang
and 6 more
August 15, 2024
Gleason grading system is dependable for quantifying prostate cancer. This paper introduces a fast multiphoton microscopic imaging method via deep learning for automatic Gleason grading. Due to the contradiction between multiphoton microscopy (MPM) imaging speed and quality, a deep learning architecture (SwinIR) is used for image super-resolution to address this issue. The quality of low-resolution image is improved, which increased the acquisition speed from 7.55s per frame to 0.24s per frame. A classification network (Swin transformer) was introduced for automated Gleason grading. The classification accuracy and F1-score achieved by training on high-resolution images are respectively 90.9% and 90.9%. For training on super-resolution images, the classification accuracy and F1-score are respectively 89.9% and 89.9%. It shows super-resolution image can provide a comparable performance to high-resolution image. Our results suggested MPM joint image super-resolution and automatic classification methods holds the potential to be a real-time clinical diagnostic tool for prostate cancer diagnosis.