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Unveiling Thymoma Typing through Hyperspectral Imaging and Deep Learning
  • +5
  • Qize Lv,
  • Ke Liang,
  • Chongxuan Tian,
  • YanHai Zhang,
  • Yunze Li,
  • Jinlin Deng,
  • WeiMing Yue,
  • Wei Li
Qize Lv
Shandong University School of Control Science and Engineering
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Ke Liang
Qilu Hospital of Shandong University
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Chongxuan Tian
Shandong University School of Control Science and Engineering
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YanHai Zhang
Shandong University School of Control Science and Engineering
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Yunze Li
Shandong University School of Control Science and Engineering
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Jinlin Deng
Shandong University School of Control Science and Engineering
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WeiMing Yue
Qilu Hospital of Shandong University
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Wei Li
Shandong University School of Control Science and Engineering

Corresponding Author:[email protected]

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Abstract

:Thymoma, a rare tumor from thymic epithelial cells, presents diagnostic challenges due to the subjective nature of traditional methods, leading to high false-negative rates and long diagnosis times. This study introduces a thymoma classification technique that integrates hyperspectral imaging with deep learning. We initially capture pathological slice images of thymoma using a hyperspectral camera and delineate regions of interest to extract spectral data. This data undergoes reflectance calibration and noise reduction. Subsequently, we transform the spectral data into two-dimensional images via the Gramian Angular Field (GAF) method. A variant residual network is then utilized to extract features and classify these images. Our results demonstrate that this model significantly enhances classification accuracy and efficiency, achieving an average accuracy of 95%. The method proves highly effective in automated thymoma diagnosis, optimizing data utilization and feature representation learning.
15 Jul 2024Submitted to Journal of Biophotonics
15 Jul 2024Submission Checks Completed
15 Jul 2024Assigned to Editor
15 Jul 2024Review(s) Completed, Editorial Evaluation Pending
15 Jul 2024Reviewer(s) Assigned
19 Jul 2024Editorial Decision: Revise Major
08 Aug 20241st Revision Received
08 Aug 2024Submission Checks Completed
08 Aug 2024Assigned to Editor
08 Aug 2024Reviewer(s) Assigned
08 Aug 2024Review(s) Completed, Editorial Evaluation Pending
15 Aug 2024Editorial Decision: Accept