The global climate crisis, unequivocally driven by human activities that increase greenhouse gases (GHGs) emissions, is proving increasingly costly and disruptive worldwide. The responsibility for and impacts of the crisis are distributed unequally among different regions, populations, and sectors. To reduce loss of life, suffering and worsened inequities, faster and more comprehensive actions must be taken to mitigate the causes and adapt to the effects. Inclusive and strategic climate actions can increase the diversity of solutions, lead to greater equity, well-being, and security, and protect the human right to a healthy and sustainable environment.