INTRODUCTION: The patients presenting with inferior wall myocardial infarction (IWMI) in particular right ventricular myocardial infarction (RVMI) primarily affects right ventricle (RV) which is poorly evaluated by echocardiographic tools. AIMS: The objective of this study is to evaluate the use of various echocardiographic parameters in assessing RV function in patients with IWMI in particular RVMI subset, correlation among various echocardiographic parameters amongst them, their association with in-hospital outcome and the role of intervention by assessing echocardiographic parameters at 3 month follow-up. The study specially focuses on pulmonary regurgitation pressure half-time (PRPHT) and right ventricular global longitudinal strain (RVGLS) as indicators of RV dysfunction apart from other conventional tools. METHODS: The study is a prospective observational analysis conducted at public sector institute in eastern India, involving 155 patients diagnosed with acute IWMI/RVMI. Patients were categorised into 2 groups based on PRPHT findings and comparison done among them and overall. Patients underwent a comprehensive evaluation including echocardiography, and coronary angiography, followed by a three-month post-treatment follow-up. Echocardiographic parameters such as left ventricular ejection fraction (LVEF), PRPHT, tricuspid annular plane systolic excursion (TAPSE), right ventricular fractional area change (RVFAC), and RVGLS were measured at both visits. RESULTS: Strong positive correlation were observed between PRPHT, TAPSE, FAC & RVGLS suggesting their use interchangeably to assess RV function. The study also explored that PRPHT had moderate positive correlation with RVGLS. It was also concluded that RVGLS as a tool is non-inferior to TAPSE and RVFAC in evaluation of RV function. It was also noted that patients with PRPHT values less than 90, TAPSE of less than 10, FAC of less than 28% and RVGLS value of less than (-12) were able to fairly predict in-hospital outcome in patients of IWMI/RVMI. The findings of present study also suggests that interventions in IWMI/RVMI has good outcomes at 3 month follow-up. CONCLUSION: The results indicate that PRPHT could serve as a valuable prognostic indicator in patients with PRPHT ≤ 100 ms. This study also suggests that PRPHT has no significant correlation with in-hospital outcome especially in patients with PRPHT >100ms. It was also noted that patients with PRPHT values less than 90, TAPSE of less than 10, FAC of less than 28% and RVGLS value of less than (-12) were able to predict adverse in-hospital outcome in patients of IWMI/RVMI. The findings of this study also suggest that PRPHT & negated RVGLS are well correlated with other standard echocardiographic measures of RV dysfunction viz. TAPSE and FAC. This study also suggests that RVGLS is non-inferior to TAPSE and FAC in evaluation of RV function in IWMI/RVMI.The findings also suggests that interventions in IWMI/RVMI has good outcomes at 3 month follow-up. RVGLS can be used as a tool to evaluate RV function in such cases.