In this paper, we introduce ZIMUX, a novel Non-Orthogonal Multiple Access (NOMA) technology designed to achieve completely interference-free, secure, and reliable transmission in future wireless networks (6G and Beyond). Unlike conventional NOMA, which struggles with increased complexity and inter-user interference, ZIMUX leverages the design of a novel type of frequency domain-based precoders to eliminate inter-user interference, while ensuring simplified receiver operations. Key benefits of ZIMUX include reduced receiver complexity, lower transmission latency, decreased signaling overhead, and enhanced security against both external and internal eavesdropping. Our design enables the seamless combination of users regardless of their distance from the base station, making it adaptable to a wide range of communication scenarios. The simplicity and efficiency of ZIMUX position it as a candidate solution for applications requiring low complexity, such as the Internet of Things (IoT), while maintaining high levels of security and performance.