Background: Trimming and shoeing of a horse should be customised to the needs and conformation of the individual which can be challenging. Objectives: To investigate the effects of tailormade three-dimensional (3D) printed plastic shoes on kinematic and kinetic parameters when compared to traditional standard steel shoes. Study design: Pilot study with cross-over design. Methods: Six horses underwent one plastic shoeing cycle, and two steel shoeing cycles (front hooves) of seven weeks in semi-randomised order. Kinematic data (accelerations measured with 3D inertial measurement units on the hooves) and kinetic data (vertical ground reaction forces and hoof balance curves determined using a pressure-force system) were collected in week 1 (W1) and week 7 (W7) of each cycle. Data were analysed using linear mixed effect models. Results: Horses shod with plastic shoes had lower peak decelerations and mean vibration frequencies in the dorsopalmar axis at W1 ([338.9±42.7; 502.2±65.4] m/s 2, p < 0.001 and [193.1±6.0; 223.5±6.3] Hz, p < 0.001) and the proximodistal axis at W7 ([690.9±53.8; 905.1±52.8] m/s 2, p < 0.001 and [172.9±5.4; 199.5±5.6] Hz, p < 0.001) compared to steel shoes. Also, the peak vertical force and vertical impulse were higher at W1 ([7.5±0.3; 6.6±0.3] N/kg, p < 0.001 and [1.53±0.052; 1.35±0.051] N∙s/kg, p = 0.001) and W7 ([7.6±0.3; 6.2±0.3] N/kg, p < 0.001 and [1.53±0.051; 1.22±0.052] N∙s/kg, p < 0.001). Horses shod with plastic shoes had a more equal pressure distribution between the toe-heel region and the medio-lateral region at W1 and W7. Main limitations: The two types of shoes differed in shape (steel: standard; plastic: frog support). Conclusions: Tailormade 3D printed plastic shoes seemed to cause less friction with the hard surface, had a dampening effect on the impact vibrations, and resulted in an increased loading of the front limbs and a more equal pressure distribution compared to steel shoes.