A case of a single oral manifestation of plasmablastic lymphoma: an initial misdiagnosisC. Debortoli1*, S. Latreche1, O. Rios1, C. Savoldelli1,2, M. Fricain11 : Department of Oral and Maxillofacial Surgery, Head and Neck Institute, University Hospital of Nice, 30 Avenue Valombrose, 06100 Nice, France2 : UR2CA, Faculty of Medicine, 31 Avenue Valombrose, 06100 Nice, France* Corresponding author : [email protected] Address : Department of Oral and Maxillofacial Surgery, Head and Neck Institute, University Hospital of Nice, 30 Avenue Valombrose, 06100 Nice, FranceKeywords : oral plasmablastic lymphoma ; plasmablastic lymphoma ; oral medicineMANUSCRIPTKey clinical messageThe initial case presentation suggested an inflammatory epulis related to the periodontal inflammatory context, but the anatomopathological diagnosis showed a diagnosis of plasmablastic lymphoma. This single manifestation is a very rare diagnosis, but plasmablastic lymphoma occurs mainly in HIV+ patients. It is therefore an important differential diagnosis to be aware of.CASE HISTORYA 56-year-old patient was referred by the internal medicine department for oral swelling. Her medical history revealed human immunodeficiency virus (HIV) (undetectable viral load ; CD4 : 250/mm3), cirrhosis, and progressive multifocal leukoencephalopathy healed fifteen years ago. She was not taking any medication and had no allergies. Her general condition was unaffected. The general examination revealed no adenopathy and no signs of inflammation and infections on the skin or oral mucosa. She only presented an asymptomatic nodular pedicled lesion between two teeth, which had been growing for 2 months. There was no bleeding on contact. Oral hygiene is improvable with the presence of dental plaque and old treatments. The teeth were not mobile and responded positively to pulp vitality tests. (Figure 1)

Mandibular bony solitary plasmacytoma: a misleading caseC. Debortoli1*, S. Latreche1, O. Rios1, C. Savoldelli1,21 : Department of Oral and Maxillofacial Surgery, Head and Neck Institute, University Hospital of Nice, 30 Avenue Valombrose, 06100 Nice, France2 : UR2CA, Faculty of Medicine, 31 Avenue Valombrose, 06100 Nice, France* Corresponding author : [email protected] Address : Department of Oral and Maxillofacial Surgery, Head and Neck Institute, University Hospital of Nice, 30 Avenue Valombrose, 06100 Nice, FranceKeywords : solitary plasmacytoma ; jaw bone ; oral plasmacytomaMANUSCRIPTKey clinical messageMandibular solitary bone plasmacytoma is a rare diagnosis, but the primary oral manifestation of a haemopathy should be considered in the face of any oral ulceration “raspberry-like”CASE HISTORYA 78-year-old woman was referred for an asymptomatic right mandibular lesion appeared three months ago, with no general health impairment. Her medical history included dyslipidemia and arterial hypertension, diseases stabilized by conventional treatment.The lesion was located in an edentulous area, from the first premolar to the retromolar trigone. Presenting as heterogeneous, erythematous, and exophytic, with a central ulceration and contact bleeding. The tongue remained mobile, with no adenopathy or involvement of the inferior alveolar nerve. (Figure 1)