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Respiratory Syncytial Virus incidence and typing in the last 6 seasons in the north of Spain (Asturias). Genetic characterization during the SARS-Cov-2 pandemic
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  • Santiago melon,
  • Susana Rojo,
  • Zulema Pérez-Martínez,
  • José María González Alba,
  • Jose Boga,
  • Cristina Ochoa-Varela,
  • Maria Agustina Alonso Álvarez,
  • Carmen Pérez Fonseca,
  • Marta María García Clemente,
  • José Gutierrez Rodriguez,
  • Estibaliz Garrido García,
  • Mercedes Rodríguez-Pérez,
  • Marta Alvarez-Arguelles
Santiago melon
Hospital Universitario Central de Asturias Laboratorio de Medicina
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Susana Rojo
Hospital Universitario Central de Asturias Laboratorio de Medicina
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Zulema Pérez-Martínez
Hospital Universitario Central de Asturias Laboratorio de Medicina
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José María González Alba
Hospital Universitario Central de Asturias Laboratorio de Medicina
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Jose Boga
Hospital Universitario Central de Asturias Laboratorio de Medicina
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Cristina Ochoa-Varela
Hospital Universitario Central de Asturias Laboratorio de Medicina
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Maria Agustina Alonso Álvarez
Hospital Universitario Central de Asturias
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Carmen Pérez Fonseca
Hospital Universitario Central de Asturias
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Marta María García Clemente
Hospital Universitario Central de Asturias
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José Gutierrez Rodriguez
Instituto de Investigacion Sanitaria del Principado de Asturias
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Estibaliz Garrido García
Hospital Universitario Central de Asturias
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Mercedes Rodríguez-Pérez
Hospital Universitario Central de Asturias Laboratorio de Medicina
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Marta Alvarez-Arguelles
Hospital Universitario Central de Asturias Laboratorio de Medicina

Corresponding Author:[email protected]

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Abstract

Respiratory syncytial virus is associated with lower respiratory tract infections. As several types and genotypes can circulate at the same time, genomic characterisation is important for timely epidemiological control and treatment measures. In the last 6 seasons (2017-2023), 191236 nasopharyngeal swabs were processed for respiratory viruses. The incidence of RSV reached 7% in the pre-pandemic season. RSV was most frequent in children under 5 years of age (12.6%), but was also significant in those over 70 years of age (5.63%). The measures taken to control SARS-Cov2 infection were useful for RSV control and the incidence decreased to 1.8%, but caused a change in the types. Pre-pandemic, the majority circulating types were RSV-B/RSV-B/RSV-A and in pandemic it was RSV-B/RSV-B. In the last season, RSV-B and RSV-A were detected in the same proportion. Genetic characterization showed three new clades. This has been taken into account in order to take the correct measures.
07 Sep 2023Submitted to Journal of Medical Virology
07 Sep 2023Submission Checks Completed
07 Sep 2023Assigned to Editor
07 Sep 2023Review(s) Completed, Editorial Evaluation Pending
07 Sep 2023Editorial Decision: Revise Major
12 Sep 20231st Revision Received
13 Sep 2023Review(s) Completed, Editorial Evaluation Pending
13 Sep 2023Submission Checks Completed
13 Sep 2023Assigned to Editor
15 Sep 2023Reviewer(s) Assigned
31 Oct 2023Editorial Decision: Revise Minor
11 Nov 20232nd Revision Received
11 Nov 2023Submission Checks Completed
11 Nov 2023Assigned to Editor
11 Nov 2023Review(s) Completed, Editorial Evaluation Pending
12 Nov 2023Reviewer(s) Assigned
15 Feb 2024Review(s) Completed, Editorial Evaluation Pending
20 Feb 2024Editorial Decision: Accept