Osteogenesis Imperfecta is a genetic disorder of connective tissue leading to bone fragility. Diagnosis of this condition can be considered during pregnancy, at birth or during childhood. Early onset forms are severe with high mortality rate. We report two cases during neonatal period in Cameroon.

We present a case of non-leukemic (lymphomatous) variant of HTLV-1 associated adult T-cell leukemia/lymphoma in a young woman. Tumor demonstrated strong and diffuse CD30 and PD-1 expression which is very unusual finding in this entity. Very good clinical response was obtained with brentuximab-containing treatment regimen.

Granulocyte-colony stimulating factor (G-CSF)-producing uterine cervical cancer (UCC) is a rare aggressive disease. We report a case of G-CSF-producing UCC treated with chemoradiotherapy. Target-capture sequencing results indicate that G-CSF-producing UCC is genetically distinct from other UCCs, warranting further research to establish specific treatment strategies.

Bosutinib is a tyrosine kinase inhibitor (TKI) approved for the management of chronic myeloid leukemia (CML). TKIs are associated with pulmonary complications but are rarely described with bosutinib. Here, we report the first description of bosutinib-induced interstitial lung disease and pleural effusion, which resolved after the discontinuation of bosutinib.

Various causes of Recurrent Acute pancreatitis have been identified in the past. This report presents a novel case of “recurrent” acute pancreatitis in the setting of superior mesenteric artery syndrome (SMAS). Thus, highlighting SMAS as a rare yet possible cause of recurrent pancreatitis facilitating early diagnosis and prompt treatment.

Drug reaction with eosinophilia and systemic symptoms is a quite unusual condition related to drug reaction. A case report of sulfasalazine-induced liver failure is described. The patient was submitted to liver transplantation. Liver transplantation is an option when DRESS is associated with acute liver failure, but the prognosis remains poor.

Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis due to various pathologies. Its prevalence ranges upto 10% and can present in different clinical picture to challenge a clinician.

The occurrence of hepatoblastoma is infrequent in children older than 5 years. Therefore, clinicians need to consider hepatoblastoma even in school-aged children or adolescents.

A 70-year-old male presented with a neglected slow growing anal wart for many years with bleeding.A deep core biopsy of the tumor confirmed a high-grade squamous intraepithelial lesion and carcinoma in situ.

Bones, lymph nodes, lungs, or liver, are the common metastatic sites for prostate cancer. However, prostate adenocarcinoma metastasis to the mandible is very rare. In this case report we present a case of a 64-year-old man with poorly differentiated prostate cancer and metastasis to the mandible.

Stab wounds are commonly seen in the emergency room of community hospitals especially in developing countries. The uniqueness of the case to be reported here was that the patient walked in the ER retaining the inflicting weapon in the wound over his back.

Naso-pharyngeal discharge as the first symptom of COVID-19 infection is presented in two cases . Appropriate diagnosis and isolation of the patients who may be at risk for covid-19 such as these cases help reduce further transmission.

An association has been reported between BP and DPP-4 inhibitors. We report three cases of DPP-4 inhibitor-associated BP, with an unfavorable course in 2 patients despite discontinuation of these drugs. Therefore, clinicians should pay close attention to the clinical course of DPP-4 inhibitor-associated BP, even after withdrawal of these drugs.

Acute basilar artery occlusions (BAO) that are not quickly recanalised may leave the patient with severe motor detriment. Efficacies of current treatments remain unclear. In our case of a 47-year-old-man presenting with quadriparesis, MRI demonstrated bilateral pontine infarct. A year after mechanical thrombectomy, he was fully ambulant.

Phantom pain (PhP)is reported by patients after limb amputation due to trauma or chronic diseases. We report the case of successful PhP treatment with pulsed radiofrequency (PRF) of the femoral and sciatic nerve. (PRF) reduced the intensity of pain for one year, improving the quality of life of the patient.

A 55-year-old man with left temporo-insulo-parietal glioblastoma was admitted because of abrupt excruciating pain in right arm and ipsilateral face. EEG showed a left central frontal rhythmic activity and complains were controlled with anti-epileptic drugs. Paroxysmal pain is an unusual manifestation of focal seizures and can be the only symptom.

Behcet’s disease (BD) is a vasculitis of unknown aetiology that is reported to accompany autoimmune diseases. We report a rare case of BD, Addison’s disease, Hashimoto’s disease, and subclinical coeliac disease all occurring in one patient which has not previously been reported.

Eosinophilic gastroenteritis (EG) can easily be misdiagnosed. We present the case of a man with abdominal pain who was EG but misdiagnosed with cholelithiasis. This case highlights the need to consider EG in the differential diagnosis of abdominal pain since a favorable result can be achieved with timely treatment.