A 31-year-old man with fever, dyspnea, abdominal pain, and jaundice has been admitted to the hospital in the southeast of Iran. Due to the presence of a pathognomonic skin lesion (Tache noire), the patient was diagnosed with Mediterranean spotted fever (MSF) and was treated with doxycycline.

A 66-year-old breast ductal carcinoma patient developed obstructive jaundice, presenting with epigastric discomfort and dark-colored urine. Contrast-enhanced computed tomography and endoscopic retrograde cholangiopancreatography revealed bile duct stenosis. Brushing cytology and tissue biopsy confirmed bile duct metastasis, and a self-expandable metallic stent was placed/replaced endoscopically, extending the patient’s life.

It is difficult to anatomically understand the three-dimensional structure of the middle ear and temporal bone during surgery, and great surgical technique are required. Therefore, complications are avoided through simulation using a three-dimensional printer, which was effective in not only safe and reliable surgery but also educating young physicians.

A woman presented with intermittent left lower abdominal pain associated with a mass and didn't have any other symptoms. During the operation, a local inflammatory mass was found in left lower quarter of abdominal cavity. There are two bony foreign bodies in it. Postoperative pathology suggested an inflammatory mass.

Immunodeficient patients are less prone to develop serious complications of COVID-19 and cytokine storm. However, they are more likely to develop opportunistic infections that can mimic the symptoms of the SARS-CoV-2. we presented a 27-year-old male case of SARS-CoV-2, who was complicated with Pneumocystis jirovecii pneumonia, following treatment with rituximab.

Fibrodysplasia ossificans progressiva is a rare condition with an estimated prevalence of one in two million individuals. The condition is characterised by widespread heterotrophic ossification of skeletal muscles and ligaments. We report the case of an eight-year-old female patient and show the radiological progression of the condition.

A 7-year-old American short-haired cat was presented with blepharospasm in the right eye. The case was finally performed with orbital exenteration, leading to the diagnosis of feline restrictive orbital myofibroblastic sarcoma. Adjuvant chemotherapy with toceranib was given for one month after surgery. However, the case died four months after surgery.

Oral mucosal lesions may persist years before diagnosis of inflammatory bowel disease (IBD) and subsequent primary sclerosing cholangitis (PSC). It may be that a dental practitioner may be the first clinician to suspect IBD. Suspect IBD; early referral and close collaboration with a gastroenterologist are recommended.

A document by Ryuhei Jinushi. Click on the document to view its contents.

Pseudo-infarction electrocardiographic changes associated with hypokalemia and hypocalcemia is rare. A 76-year-old lady with previous total thyroidectomy presented with unspecific symptoms. Electrocardiogram demonstrated ST-elevation. She was found to have hypokalemia and hypocalcemia associated with delayed onset hypoparathyroidism. This may suggest possible etiologies like coronary vasospasm and catecholamine-associated myocardial injury.

The nicotinic symptom in Organo-Phosphate (OP) poisoning is an unusual presentation in an adult, as in our case of a 38-year-old man who also experienced decreased motor power of all limbs and diffuses fasciculation of the tongue and lower limbs.

Splenic hematoma following an acute pancreatitis is a rare complication which is thought to be due to the distribution of pancreatic exudates to the spleen. We presented a case of a 44-year-old patient with acute pancreatitis who developed splenic hematoma. He responded well to conservative management and the hematoma resolved.

The use of endocardial pacing in patients with univentricular hearts is limited. However, it may be the better option when the risk of surgery is high. We report a case of complete heart block who underwent left ventricular endocardial pacing due to the high risk of epicardial lead placement.

Transoral robotic surgery (TORS) has evolved into a common surgical modality used to treat primarily oropharyngeal malignant and benign pathologies. The single port Intuitive Surgical da Vinci surgical robotics system facilitates access to the hypopharynx and cervical esophagus. We aim to describe our approach and advantages of the technique.

A 22-year-old male was admitted to our hospital after taking 2450 mg of pilsicainide. On admission, the patient was in cardiac arrest, and percutaneous cardiopulmonary support was introduced to maintain his circulation. After three days of intensive care, he was no impaired consciousness and transferred another hospital for psychological problem.

Here we present a diagnostically challenging Bing-Neel Syndrome (BNS) case successfully treated with systemic chemoimmunotherapy and ibrutinib, with remarkable clinical response. BNS is an extremely rare direct central nervous system infiltration by malignant lymphoplasmocytic lymphoma cells in patients with Waldenstroms macroglobulinaemia.

Soft tissue candidiasis is an opportunistic infection that occurs in immunocompromised patients and must always be diagnosed and treated as soon as possible. In this case report, the patient is a 14-year-old boy with acute myeloid leukemia M3-type who presented with numerous soft tissue and hepatosplenic candidal abscesses.

Chronic kidney disease associated with incidental tuberculoma represents one of the rarest conditions occurring worldwide. Among tuberculous patients, only 1% show Central Nervous System involvement. We present a case of 45-year-old male with CKD who presented with seizure, diagnosed to have incidental Tuberculoma