Retinal arterial macroaneurysm shows rapid vision loss when rupture occurs; therefore, preventive photocoagulation should be considered, if necessary.

Patients with relapsed follicular lymphoma who do not respond to CAR-T have a poor outcome. We present a case of refractory follicular lymphoma who relapsed after two CAR-T infusions and achieved a complete remission after treatment with obinutuzumab and lenalidomide. This represents a promising treatment option in the post-CAR-T setting.

A 73-year-old man underwent a stage Ⅱ sigmoid colon cancer resection. Careful monitoring was undertaken, and no evidence of metastasis or anastomotic recurrence was noted until 51 months later. Anal examination revealed a pink, firm perianal tumor histologically identified as a metastasis of the colon adenocarcinoma.

Primary invasive breast carcinoma with neuroendocrine differentiation is an uncommon presentation. We hereby report a case diagnosed as invasive ductal carcinoma with neuroendocrine differentiation in a 52-year-old female who presented with a painless right breast lump.

Coronavirus disease 2019 (COVID-19) vaccination is reportedly safe and effective. The histologic features of post-COVID-19 vaccination myocarditis are unknown. We present a 77-year-old Japanese woman who was diagnosed with eosinophilic myocarditis using endomyocardial biopsy, 7 days after receiving the second dose of BNT162b2 COVID-19 vaccine. Methylprednisolone pulse therapy was effective.

Cutaneous squamous cell carcinoma (cSCC) is the second most common non melanoma skin cancer after Basal cell carcinoma, characterised by the malignant proliferation of epidermal keratinocytes. We report a case of an inoperable cSCC of the scalp extending into the sagittal sinus, now responding well to the monoclonal antibody Cemiplimab.

Paroxysmal dysarthria and Ataxia (PDA) is a rare neurological manifestation of stereotyped attacks of sudden ataxic symptoms lasts for few seconds to minutes, of variable frequency. We report a case of PDA in a 61 years old male with an isolated homogenously enhancing solitary midbrain lesion and positive HLA-B51.

COVID-19 infection results in extensive organ dysfunction. Thrombotic problems linked to COVID--19 disease is common and can affect the retina. We will report a case of retina hemorrhage with possibility of linkage between COVID-19 infection or immunization to determine whether these abnormalities are causal or coincidental.

We report the case of a 51-year-old Caucasian woman who developed a pulmonary embolism in the absence of any pre-existing risk factors for VTE, three weeks following clozapine initiation for treatment resistant paranoid schizophrenia. She was initially misdiagnosed and treated for suspected COVID-19 infection.

We report a case based on simultaneous occurrence of Waldenström macroglobulinemia, myeloma and amyloidosis as a collision neoplasm. The strangeness and severity of the case presented a diagnostic and therapeutic challenge, which required individualised treatment and close follow-up to achieved stringent complete response.

Temporomandibular Joint Ankylosis(TMJA) may manifest in patients with several predisposing systemic conditions. A case of extraarticular TMJA is presented in a patient diagnosed with Fibrodysplasia Ossificans Progressive(FOP) is presented. The features, diagnosis and management of TMJA superimposed on this condition is presented through a qualitative systematic review of literature.

The World Health Organization classifies odontomas as odontogenic tumors.There are two variants of odontomas: complex and compound. Complex odontomas are made of an anarchic assembly of mineralized tissue and dental pulp; while compound odontomas are consisting of a set of rudimentary teeth. They rarely show the features of both ty

Although under-reported, hemolytic anemia is common with dapsone therapy. However, it is prudent to screen underlying G6PD deficiency to prevent potentially life-threatening episode of intravascular hemolysis in leprosy.

Synchronous ovarian and endometrial tumor is a rare entity. We report a case of a 38-year woman with an endometrioid variant of synchronous primary endometrial and left ovarian carcinoma. Patient underwent total abdominal hysterectomy with bilateral salphingo-oophorectomy with lymphadenectomy and is disease free till 9 months.

Anophthalmia AO and microphthalmia MO have both heritable and environmental causes. The proband described in this study was a 32-year-old symptomatic The detected homozygous canonical splice site variant in the TENM3 gene has not been reported up to now for its pathogenicity and can be considered as a novel mutation.

Gastroduodenal fistula (GDF) is a rare endoscopy finding that can be acquired or congenital. We present the case of a 65-year-old male without medical past history who was admitted for gastrointestinal bleeding secondary to peptic ulcer. The case shows an acquired double pylorus, due to pre pyloric ulcer.

This report describes the case of an 84-year-old male who was brought to the emergency room because a dental bur was swallowed accidentally during a dental procedure. The foreign body was successfully removed by gastroenterologists endoscopically 8 days after the ingestion and was identified as a 2-cm-long dental bur.

Neuroendocrine tumors have a wide range of malignant potential. These tumors infrequently metastasize to the orbit. We report the case of a 61-year-old man who presented with unilateral recurrent panuveitis related to choroidal metastasis. Explorations led to the diagnosis of pancreatic neuroendocrine carcinoma as the primary tumor.