The Nairovirus causing the Crimean Congo Hemorrhagic Fever (CCHF) is transferred mainly via ticks and farm animals. Its incidence is spread over several countries broadly categorized into continents, including Europe, Asia, and Africa. This editorial is shedding light on this concerning pathogen and suggesting several strategies to tackle it.

A 35 years old female presented to the ED with severe pain and right thigh discharge for 2 days. She gave a history of chickenpox 2 weeks ago and received ibuprofen for excruciating pain. She was immediately diagnosed with necrotizing fasciitis and shock.

Influenza A and B are the most common causes of respiratory tract-restricted acute viral disease. Each year, it is estimated that around 16% of children aged 5 to 17 are hospitalized. Baloxavir Marboxil has the potential to be an innovative alternative to the existing standard of therapy for these individuals.

This is a 3-week-old female, her presenting complaints were low-grade fever and a blocked nose for one day. Eventually, she developed progressive desaturation, hypotension, and poor perfusion due to severe pulmonary hemorrhage. Then, she developed cardiac arrest and was declared dead.

During the COVID-19 pandemic, multiple skin manifestations have been described. These include an urticarial rash, morbilliform rash, maculopapular rash, vascular lesions, and varicella-like eruptions. A 30-year-old woman presented with a mild cough, then hives and pruritic rash for 3 days, followed by fever, dyspepsia, and throat pain for one day.

Background: The BioNTech-Pfizer vaccine is the only vaccine offered to children among all available vaccines. However, limited evidence is available about the clinical outcomes of COVID-19 vaccines, especially among children and adolescents. This review offers a comprehensive and up-to-date overview of the BioNTech-Pfizer vaccine’s current information on children and adolescents. Methods: The review was conducted following the PRISMA guidelines; a comprehensive search was performed in PubMed, Scopus, MEDLINE, and EMBASE databases for research publications COVID-19 published between December 2019 and October 2021. All studies reporting on the outcomes of vaccinating children in their respective institutes were included. Results: A total of 78 vaccinated children and adolescents from 6 studies were included. The majority of symptomatic vaccinated pediatrics were males (71%). The mean age was 15.6 years, and the BMI was 24.1. The most common clinical symptoms were found in chest pain (35%), fever (32%), and myalgia (17%). The most common cardiac symptom in the EKG results was ST elevation, and 35% of vaccinated pediatrics had elevated serum troponin. The hospitalization, including ICU admission, was lower than in unvaccinated groups. Statistically significant associations (P = <0.05) were found in two symptoms (fever and headache) between the vaccinated and non-vaccinated pediatric groups. Conclusions: Although we found better outcomes in the vaccinated group versus the non-vaccinated pediatric group, more studies are still crucial to further understand the specific etiology underlying post-vaccination, particularly myocarditis, psychological impact, and other cardiac clinical symptoms in children and adolescents after receiving the BioNTech-Pfizer vaccine.

This report describes a case of a 50-year-old man with hypertension who was admitted with a history of fever, chills, and shortness of breath and tested positive for COVID-19. Shortly after resolving his ARDS, he developed an adipsic hypernatremia with associated confusion, lethargy, and weakness.

Patients with pleural effusion are mostly presenting with shortness of breath and pleuritic chest pain. This report describes a case of PE who presented with left shoulder pain and was found to have rapidly accumulating massive effusion within 24 hours of presentation. Thoracocentesis was performed a showed an exudative picture

Three years old boy presented with recurrent severe abdominal pain. He was treated for constipation and the pain resolved. Later he developed a limitation of neck movements. Investigations revealed a spinal cord mass. After surgical resection, histopathology confirmed pilocytic astrocytoma.

This is a case of an elderly female with comorbidities and a history of cardiac transplant 13 years back, presented with diarrhea and diagnosed with COVID-19. She was hospitalized and found to have a cardiac injury and urinary tract infection, treated with antibiotics, antivirals, immunosuppressives, and required non-invasive ventilatory support.

Tension pneumomediastinum (TPM) is a rare but potentially fatal clinical entity. This leads to leakage of air into the mediastinal cavity and increased pressure on thoracic vessels, respiratory tract, and the heart. We report a series of five cases of COVID-19 complicating into acute respiratory distress syndrome and developing TPM.

This report describes a case of 45 years old male patient who tested positive for COVID-19 presented to the emergency department on March 2021 complaining of fever, cough, runny nose, and shortness of breath. The patient denied any history of nausea or diarrhea who has eventually developed favipiravir-induced nephrotoxicity.