Synthetic biology is the engineering approach to edit or write the genome aiming to design the biological devices (promoters, transcription factors, TFBS, terminators etc.) of an organism to achieve the improved properties, while, metabolic engineering aiming to engineer the microbes to produce metabolites on industrial scale through recombinant DNA technologies. Recently, both synthetic biology and metabolic engineering fields are growing quickly and are used to produce metabolites of interest. The main theme of Synthetic Biology – Metabolic Engineering book is to review the tools and techniques used in synthetic biology and metabolic engineering to design and engineer the microbes to produce value-added metabolites and its application in industrial biotechnology. The book is written by the world-renowned metabolic engineers and synthetic biologists in series of Advances in Biochemical Engineering/Biotechnology and primarily elaborates the synergy between metabolic engineering and synthetic biology.