There is increasing evidence that COVID-19 infection predisposes to thromboembolism. A 71 years-old male patient was admitted to ICU for COVID-19 related pneumonia. He developed a high troponin rise up to 6715 ng/L. By transthoracic echocardiography, we found akinesia of the full right ventricular apex with a mobile hyperechogenic mass, highly suggestive of thrombus. Unfractionated Heparin was started immediately. A subsequent echocardiogram showed no mass. To our knowledge, this is the first case showing a thrombus formation in the context of right ventricular apical akinesia in COVID-19 patients. There is upcoming evidence that the clinical relevance of thromboembolic complications may be a serious issue in COVID-19 patients even in the absence of any obvious risk factor. Our case clearly demonstrate that, in patients with COVID-19 infection and troponin rise, echocardiography should be performed to rule out possible thrombotic complications