Uğur Karagöz

and 4 more

Background: Electrocardiographic left ventricular hypertrophy (ECG LVH) has a prognostic value for cardiovascular diseases. Pathological processes that cause development of left ventricular hypertrophy (LVH) also leads to remodeling and dysfunction of the left atrium (LA). Atrial functions can be evaluated by 2D speckle tracking echocardiography. In our study, we aimed to investigate whether the ECG LVH is associated with left atrial strain. Methods: Sixty two patients with LVH according to echocardiographic left ventricle mass index were included in the study. ECG LVH was defined according to: Sokolow- Lyon voltage SV1+RV5/RV6>35mm; Cornell voltage RaVL+SV3>28 mm (for men) >20mm (for women); or Cornell product (SV3+RAVL+(for women 8 mm)) x QRS duration)>2440 mmxms criteria. Patients were categorised into two groups according to presence or absence of ECG LVH. Association between left atrial strain values and ECG findings were evaluated. Results: The mean age of the patients were 58.3±10.1 years; 40.3% were women; 91,9% had hypertension; 35.5% had diabetes. Nineteen patients (30.6%) had ECG LVH according to Sokolow-Lyon voltage, Cornell voltage or Cornell product. Left atrial reservoir, conduit and contraction strains were significantly lower in patients with ECG LVH (p<0.001). Additionally, there was statistically significant correlation between all three phases of left atrial strain values and presence of Sokolow-Lyon voltage (reservoir phase r:-0.389 p<0.01; conduit phase, r:-0.273 p<0.05; contraction phase r:-0.359 p<0.01) Cornell voltage (reservoir phase r:-0.49 p<0.001; conduit phase r:-0.432 p<0.001; contraction phase r:-0. 339 p<0.01) Cornell product (reservoir phase r:-0.471 p<0.001; conduit phase r:-0.387 p<0.01; contraction phase r:-0.362 p<0.01). Conclusion: ECG LVH was associated with left atrial strain and therefore it can be a useful tool to predict left atrial dysfunction.

Özgen Şafak

and 17 more

Aim Doppler echocardiography has become the standard imaging modality for diastolic function and provide pathophysiological insight into systolic and diastolic heart failure. In this study we aimed to obtain normal echocardiographic Doppler parameters of healthy Turkish population. Methods Among 31 collaborating institutions from all regions of Turkey, 1154 healthy volunteers were enrolled in this study. Predefined protocols were used for all participants during echocardiographic examination and The American Society of Echocardiography and European Association of Cardiovascular Imaging recommendations were used for echocardiographic Doppler measurements. Results A total of 967 healthy participants were enrolled in this study after applying exclusion criteria. Echocardiographic examination was obtained from all subjects following predefined protocols. Mitral E wave velocity and E/A ratio were higher in females and decreased progressively in advancing ages. E wave deceleration time and A wave velocity were increased with aging. Assessment of tissue Doppler velocities showed that left ventricular lateral e’, septal e’ and septal s’ were higher in younger subjects and in females. E/e’ ratio was increased progressively with advancing decades. Right ventricular e’and s’ were decreased but a’ was increased with increasing age. Septal e’ lower than 8 cm/s was 1.9% in the fifth decade and 13.7% in ages older than 50-years. The E/e’ ratio greater than 15 (and also 13) was not found. Conclusion This study, for the first time, provides echocardiographic reference ranges for normal cardiac Doppler data in healthy Turkish population which will be useful in routine clinical practice as well as in future clinical trials.