We present a patient with congenital Glanzmann Thrombasthenia, who developed recurrent venous thrombosis. Over time, she developed the clinical picture of a myeloproliferative neoplasm, being JAK2 positive. This case clearly indicates that the platelet aIIbĪ²III integrin (lacking in Glanzmann thrombasthenia) does not have a role in thrombosis in MPN