Wheezing is often occurred in infants and young children with respiratory infections. For children with recurrent wheezing, after controlling their wheezing, they should be alert to rare diseases. Here, We report a case of wheezing following the application of the patent ductus arteriosus occlusion device ADOII (AGA Medical Corporation, Golden Valley,MN) with the occlusion device pressing against the inner diameter of the adjacent left main bronchus. After the pressure end of the occluder was removed, the child’s wheezing was effectively relieved