Cardiac myxoma (CM) is a rare cardiac disease, accounts for approximately 70% of the adult cardiac tumors, with the majority located in the left atrium and less commonly in the right atrium. Rarely myxomas may be present in right ventricular, biatrial, left ventricular, right ventricular outflow tract or heart valves. Our study described clinical and echocardiographic characteristics of 5 patients with echocardiographic diagnosis of rare CMs, among them pulmonary valve (PV) myxoma was never been reported before. Therefore, cardiac tumors developed in unusual locations should be considered to exclude the possibility of myxoma.