S) score, posterior ethmoid sinus (PES) score, sphenoid sinus (SS) score, ethmoid sinus score/maxillary sinus score (ES/MS) ratio and posterior ethmoid sinus score/anterior ethmoid sinus score (PES/AES) ratio were significantly higher in the B-high subgroup. Logistic regression analyses disclosed that comparing with other sinus CT parameters, OC score was an independent predictor for systemic eosinophilia. There was a moderate correlation between OC score and the level of blood eosinophil (r=0.57, P<0.001). Conclusion: Olfactory cleft opacification shown in paranasal sinus CT may be a marker for the phenotype of CRSwNP with systemic eosinophilia, which appears to be closely related to olfactory dysfunction.