Purpose: Merozoites are the only extracellular form of blood stage parasites, making it a worthwhile target for vaccine and drug development. Multiple invasins that are stored in the merozoite apical organelles, are secreted just prior to invasion, and mediates its interaction with host cell. A comprehensive identification of all these secreted invasins is lacking and this study addresses that gap. Experimental design: Pf3D7 merozoites were enriched and were triggered to discharge apical organelle contents by exposure to ionic conditions mimicking that of blood plasma. The secreted proteins were separated from cellular contents and both the fractions were subjected to proteomic analysis. Also, the identified secreted proteins were subjected to gene ontology and PPI network analysis. Results: A total of 63 proteins were identified in the secretory fraction with membrane and apical organellar localization. This includes various MSPs, micronemal EBAs, various rhoptry bulb proteins, which plays a crucial role in initial and late attachment of the merozoite with the RBC, and harboured multiple linear B cell epitopes. Conclusion and clinical relevance: We, for the first time, report the secretory repertoire of merozoite. This information can be utilized to develop better invasion blocking multisubunit vaccines, comprising of immunological epitopes from several secreted invasins.