IntroductionPorokeratosis (PK) is an epidermal disorder of keratinization caused by mevalonate pathway abnormalities. 1 Different clinical subtypes of PK are described. The common types include disseminated Superficial Actinic Porokeratosis, porokeratosis of Mibelli, and Linear porokeratosis. Disseminated superficial porokeratosis, eruptive disseminated porokeratosis, porokeratosis palmaris et plantaris disseminate, punctate porokeratosis, porokeratosis ptychotropica, penoscrotal porokeratosis, and Follicular porokeratosis (FPK) are the less common types of PK. 2 The clinical appearance, predilection site, and symptoms vary in various forms of PK.2 Cornoid lamella is the common histopathologic feature in all types of PK. 1, 2Follicular porokeratosis is a rare form of PK, characterized by the cornoid lamella filling the hair follicle infundibulum.3 Follicular porokeratosis may be concomitant with other PK forms 4 or occurs as pure FPK.5 Although most of the FPK cases are localized lesions3, 6-9, more diffuse distribution of lesions is reported in a few patients. 5, 10 The scalp is not a common site for FPK 3, 5, 11, and according to available sources, only one of the scalp FPK cases caused alopecia.5 Although diabetes mellitus type 2 accompanied some cases of porokeratosis 12, 13, we could not find any case of FPK associated with diabetes mellitus.Herein, we report a case of extensive FPK with spicules that caused alopecia of the scalp hair in a diabetic woman.

Cardiofaciocutaneous syndrome is a rare genetic disorder. It is characterized by craniofacial dysmorphism, congenital heart disease, ectodermal abnormalities, developmental delay, and central nervous system disorders. We discuss the case of an 11-year-old boy with cardiofaciocutaneous syndrome presenting with ulerythema ophryogenes and phenotypic features similar to Noonan syndrome.