INTRODUCTION Breast cancer is currently one of the most commonly diagnosed cancer and the fifth most common cause of cancer-related deaths with an estimated number of 2.3 million new cases worldwide according to the GLOBOCAN 2020 data.1 Breast cancer is detected early in recent years by screening, and have an advanced treatment options including surgery, radiotherapy and chemo-endocrine therapy. So, these patients have a better survival rate. But, some patients still present with locally advanced, metastatic or recurrent breast cancer. The resection of locally advanced or recurrent breast carcinomas frequently results in large chest-wall skin defects. Reconstruction of large defects following mastectomy remains a technical challenge for oncosurgeons and plastic surgeons.2 While skin grafts are non-aesthetic, other local fascio-cutaneous and pedicled flaps are often inadequate for full coverage. Free flaps are increasingly used for aesthetic breast reconstruction,2 but they often require expertise, equipment and time that are not frequently available in a setting like ours. Since, a large number of breast cancer patients often present in late stage with skin involvement, operability and outcome are often determined by whether negative margins could be achieved with satisfactory soft tissue reconstruction. As of late, we have used external oblique myocutaneous (EOM) flap as a means of closing such large defects with encouraging results.