This paper proposes orthogonal time sequency multiplexing (OTSM), a novel single carrier modulation scheme based on the well known Walsh-Hadamard transform (WHT) combined with row-column interleaving, and zero padding (ZP) between blocks in the time-domain. The information symbols in OTSM are multiplexed in the delay and sequency domain using a cascade of time-division and Walsh-Hadamard (sequency) multiplexing. By using the WHT for transmission and reception, the modulation and demodulation steps do not require any complex multiplications. We then propose two low-complexity detectors: (i) a simpler non-iterative detector based on a single tap minimum mean square time-frequency domain equalizer and (ii) an iterative time-domain detector. We demonstrate, via numerical simulations, that the proposed modulation scheme offers high performance gains over orthogonal frequency division multiplexing (OFDM) and exhibits the same performance of orthogonal time frequency space (OTFS) modulation, but with lower complexity. In proposing OTSM, along with simple detection schemes, we offer the lowest complexity solution to achieving reliable communication in high mobility wireless channels, as compared to the available schemes published so far in the literature.