Wound healing in movable parts poses challenges due to frequent activities, leading to delayed recovery and heightened susceptibility to bacterial infections and inflammation. Although hydrogel-based dressings have been explored, their therapeutic effectiveness is limited by their poor resistance to stimuli and low mechanical strength. Here, to address this issue, we present a novel self-activated multifunctional PHC bandage that not only prevents bacterial infection but also capitalizes on the inherent mobility of the affected area to expedite the wound healing process. The PHC bandage was fabricated by incorporating photothermal copper bismuth sulfide (Cu3BiS3) nanoparticles (NPs) into piezoelectric and pyroelectric polyvinylidene fluoride (PVDF). Upon exposure to near-infrared light, the embedded Cu3BiS3 nanoparticles generate localized heat, activating the PVDF and inducing the production of abundant reactive oxygen species for bacterial inactivation. Furthermore, the continuous movement of the wounded area triggers the PVDF to generate a sustained electrical field, promoting cell migration and proliferation to facilitate wound healing. Importantly, the robust encapsulation of PVDF ensures secure containment of the loaded Cu3BiS3 nanoparticles, improving the biocompatibility and sustainable utilization of this innovative wound dressing. This innovative design offers a promising and effective solution to improve wound healing in movable parts, potentially revolutionizing wound care technology.