The paper focuses on the simulation and testing of a hybrid solid desiccant vapor compression air conditioning system under different hot-humid climates. The simulation is carried out by a BLUEJ programming framework. Air at the lowest achievable air temperatures from a solid desiccant cooling system is supplied to a standard vapor compression air conditioning system. The cooling capacities of the hybrid system under three modes indicating different supply air conditions to the cabin, are reported in the paper. From the performance study, it is inferred that the hybrid system provides significant energy savings compared to a standard air conditioner, especially in hot-humid ambient conditions. The solid desiccant cooling system thus establishes itself as an effective pre-cooler unit to a standard vapor compression air conditioning system.