It is commonly known that both different brain regions and brainwaves are associated with different activities. This paper attempts to determine and analyze the differences in region activation and brainwave manifestation between a subject with Autism Spectrum Disorder (ASD) and a neurotypical subject regarding the working memory for spatial information. I hypothesized that variances in temporal and frontal lobe activation as well as beta and gamma wave activation. Data from a spatial memory test was captured, purified, plotted, and analyzed through Muse, MATLAB, and EEGLAB. I found inverse activation patterns between the frontal and temporal regions of the neurotypical and ASD brain. The ASD brain presented cumulatively lower-level delta, theta, alpha, and gamma waves. The neurotypical brain featured significantly more powerful beta waves. Increasing the subject pool and the number of electrodes would better reinforce the results of this study.