Sinem Unal1,2#, Stéphanie Dublanc3#, Hailun Li1,2, Camille Soudée1,2,Whipple Consortium, Vivien Béziat1,2,4, Guillaume Vogt1,2,4, Xavier Puéchal5,Jean-Laurent Casanova1,2,4,6,7,§, Jacinta Bustamante1,2,4,8,§,@, Jérémie Rosain1,2,4,8,§,@1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Inserm U1163, Necker Hospital for Sick Children, Paris, France, EU2University of Paris Cité, Imagine Institute, Paris, France, EU3Departmental of Rheumatology, Libourne Hospital, Libourne, France, EU4St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, New York, USA5National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP) Centre, University of Paris Cité, Paris, France, EU6Howard Hughes Medical Institute, New York, NY, USA7Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France, EU8Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France, EU*,§equal contributions@Correspondence: [email protected] (J.B.) or [email protected] (J.R.)