Patients with systemic lupus erythematous (SLE) are at higher risk of malignant lymphomas, particularly non-Hodgkin lymphoma. Primary central nervous system lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin lymphoma. In adults, about twenty cases have been reported. Malignancy in pediatric-onset patients with SLE has been less extensively studied.

Adrenergic myocarditis is a very rare manifestation of pheochromocytoma. On the other hand, due to the pandemic situation, COVID-19 pneumonia is now considered a differential diagnosis of patients with dyspnea. This case illustrates diagnostic difficulties of such uncommon disease during this pandemic situation.

Non-islet cell tumor hypoglycemia (NICTH) is a rare but severe complication of malignancy. We present the case of 55 year old man who was admitted for severe hypoglycemia. The diagnosis of insulinoma was ruled out. After clinical work-ups, we made the diagnosis of metastatic HCC with production of IGF-2.